Polycystic kidney disease is an inherited kidney disorder that triggers unusual cysts grow and to develop. Studies have revealed kidney damage is reduced by cannabis and helps handle unwanted side effects like high blood pressure and pain.
Review of Polycystic Kidney Disease
Polycystic kidney disease (PKD) is an inherited disorder that creates clusters of cysts to grow in the kidneys. The cysts are full of fluid and will enlarge the kidneys, replacing much of the standard structure. The strange contour contributes to chronic kidney disease, which could then over time lead to even kidney failure and decreased kidney function. PKD cysts can also develop in the liver and elsewhere through the body while most cysts develop in the kidneys.
Genetic defects that are inherited cause polycystic kidney disease. In rare instances, a mutated gene could possibly be the cause of the disease. You will find two kinds of polycystic kidney disease, each of which is caused by distinct genetic flaws. Autosomal recessive polycystic kidney disease (ARPKD) is a less common kind of PKD that ordinarily develops shortly after birth or during childhood. Both parents must have unusual genes for this sort of ailment.
High blood pressure is normally caused by PKD. Other symptoms caused by the disease include kidney stones, back or side pain, headaches, blood in urine, an increase in abdomen size, frequent urination, urinary tract or kidney infections and kidney failure. Brain aneurysms, heart valve abnormalities, colon problems and long-term pain can also grow from your ailment.
There is no remedy for polycystic kidney disease, but lifestyle changes and medical treatments can help handle blood pressure and reduce kidney damage. Controlling high blood pressure can, the progress of subsequent kidney damage and the disease delayed. Drug is frequently used to handle persistent pain. Additional treatments are essential if blood in the urine, bladder or kidney diseases, kidney failure or aneurysms, develop.
Findings: Ramifications of Cannabis on Polycystic Kidney Disease
While clinical studies on cannabis’ effect on polycystic kidney disease are lacking, findings in preclinical studies indicate therapeutic benefits could be offered by cannabinoids found in cannabis for treating kidney disease. One animal study found a significant cannabinoid within cannabis, cannabidiol (CBD) efficiently reduced oxidative stress, inflammation and cell death in the kidney and improved renal function, causing the researchers to conclude CBD may be capable of preventing kidney disease (Pan, et al., 2009).
Cannabis could also restrict kidney damage brought on by polycystic kidney disease by potentially lowering blood pressure. CBD specifically has shown supply vasodilation, which researchers found allowed for greater blood circulation and reduced damage (Stanley, Hind & O’Sullivan, 2013).
In addition, cannabis can help polycystic kidney disease patients manage their chronic pain degrees. Due to cannabis’ effectiveness, surveys have unearthed that use is common among those experiencing long-term pain (Ware, et al., 2003). Cannabis has additionally been shown to provide a healing function for head aches, which are common in people who have polycystic kidney disease (Baron, 2015).